NCERT Solutions for Class 12 Biology Chapter 10: Biotechnology and Its Applications
NCERT Solutions for Class 12 Biology Chapter 10 – Biotechnology and Its Applications help students see how the tools learned in Chapter 9 are put to real-world use. Agriculture, medicine, and diagnostics all benefit from biotechnology, and this chapter explains how. Myclass24 presents accurate, exam-ready solutions to every question in this chapter. Students must check all subjects NCERT solutions for Class 12 and all the chapters of NCERT solutions for class 12 Biology.
Find the PDF of NCERT Solutions for Class 12 Biology Chapter 10
Students can download the free PDF of NCERT Solutions for Class 12 Biology Chapter 10 – Biotechnology and Its Applications from the Myclass24 website. The PDF is available in a clean, printable format. All solutions are structured to match the CBSE marking scheme, making them ideal for last-minute revision and exam preparation.
Chapter 10 Details at a Glance
Detail | Information |
Chapter Number | Chapter 10 |
Chapter Name | Biotechnology and Its Applications |
Subject | Biology |
Class | Class 12 |
Board | CBSE / NCERT |
Total Exercises | 3 (In-text + End-of-chapter) |
Key Topics | Bt crops, RNA interference, insulin production, gene therapy, GMOs, ethical issues |
Difficulty Level | Moderate |
About Chapter 10: Biotechnology and Its Applications
This chapter shifts from theory to application. After understanding how recombinant DNA technology works, students now see it in action — from the fields of Punjab to research labs producing life-saving drugs. The chapter is divided into three main application areas: agriculture, medicine, and diagnostics.
In agriculture, the chapter discusses genetically modified organisms (GMOs) and how they are changing crop production. Bt cotton is the most commonly cited example — the bacterium Bacillus thuringiensis produces a protein called Bt toxin that kills certain insects. When the gene for this toxin is inserted into the cotton plant, the plant itself becomes insect-resistant, reducing the need for chemical pesticides. This is a highly tested topic and students must be able to explain why Bt toxin doesn't harm humans but kills insects.
RNA Interference and Pest Resistance
RNA interference (RNAi) is a newer concept introduced in this chapter. It involves silencing specific genes using complementary dsRNA molecules. The chapter uses the example of nematode Meloidogyne incognita, a parasitic worm that attacks tobacco roots. By introducing dsRNA specific to the nematode's genes into the plant, the worm's RNA is degraded, killing it without any chemical pesticide. This concept is conceptually challenging but extremely important for both boards and NEET.
Other GM crops discussed include Flavr Savr tomatoes (engineered for longer shelf life by silencing the polygalacturonase gene) and golden rice (engineered to produce beta-carotene, addressing Vitamin A deficiency).
Medical Applications and Ethical Concerns
In medicine, the chapter covers the production of human insulin using rDNA technology. Earlier, insulin was extracted from pig and cow pancreas, which caused allergic reactions in some patients. Today, the gene for human insulin is inserted into E. coli or yeast, and the resulting recombinant insulin (like Humulin) is used worldwide. The two chains — A and B — and their assembly through C peptide removal must be understood in detail.
Gene therapy is discussed as a way to correct genetic disorders by inserting a correct copy of a gene. ADA (Adenosine Deaminase) deficiency is the classic example used — the first gene therapy trial was conducted in a child with this condition.
The chapter ends with ethical, social, and legal concerns related to GMOs and patenting of biological material. Students are expected to critically analyse these concerns rather than just recall them.
Key Topics Covered in Chapter 10
Bt cotton — Bt toxin mechanism, why it is safe for mammals
RNA interference (RNAi) — silencing nematode genes in tobacco plants
Golden rice and Flavr Savr tomato as GM crop examples
Recombinant human insulin production — proinsulin, chain A and B
Gene therapy — ADA deficiency case study
Ethical, legal, and social concerns (ELSI) around GMOs and biopiracy
Myclass24's solutions for Chapter 10 are designed to help students answer application-based questions effectively. Each answer is structured to earn full marks while building genuine understanding of how biotechnology shapes the world around us.