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Which type of proteins are formed by free and attached ribosomes?

GeneralClass 12AllAnswered 27 Mar 2026
Answer

Ribosome Location

Proteins Synthesized

Destination

Free ribosomes (in cytosol)

Structural proteins, enzymes for cytoplasmic functions

Cytoplasm, nucleus, mitochondria, chloroplasts, peroxisomes

Attached ribosomes (on RER)

Secretory proteins, membrane proteins, lysosomal enzymes

ER lumen → Golgi → secretory vesicles, lysosomes, plasma membrane, or exocytosis

Signal hypothesis: Proteins destined for ER have N-terminal signal sequence recognized by Signal Recognition Particle (SRP), directing ribosome to ER membrane.

General · Class 12