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Though we say that aerobic respiration uses oxygen, none of the pathways (glycolysis, Krebs cycle) directly utilize it. Where is oxygen used?

GeneralClass 12AllAnswered 27 Mar 2026
Answer

 Oxygen acts as the terminal electron acceptor in the Electron Transport System (ETS). At the end of the chain, oxygen combines with electrons and protons (H⁺) to form water (H₂O).

Reaction:
 ½O₂ + 2H⁺ + 2e⁻ → H₂O

This step is crucial; without oxygen, the entire ETS halts, and aerobic respiration cannot proceed.

General · Class 12