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Give the differences between SER and RER.

GeneralClass 12AllAnswered 27 Mar 2026
Answer

Feature

Smooth ER (SER)

Rough ER (RER)

Ribosomes

Absent

Present (attached to cytoplasmic surface)

Appearance

Tubular network

Flattened cisternae (sacs)

Primary function

Lipid synthesis (phospholipids, steroids)

Protein synthesis (secretory and membrane proteins)

Abundance

High in steroid-producing cells (adrenal cortex, gonads, liver)

High in protein-secreting cells (pancreatic cells, plasma cells)

Additional roles

Detoxification (liver), Ca²⁺ storage (muscle), glycogen metabolism

Protein folding, glycosylation, transport to Golgi

Both form a continuous membrane system and work coordinately in cellular metabolism.

General · Class 12